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Ronymeran
Posté le:
13/6/2024 05:29
Sujet du message:
Fildena 25 mg
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How does Fildena 25 mg affect the body's hormonal regulation?


Fildena 25 mg contains Sildenafil citrate, a medication primarily used to treat erectile dysfunction (ED) by increasing blood flow to the penis. It does not directly affect the body's hormonal regulation in terms of altering hormone levels. Here's a breakdown of how Fildena 25 mg works and its effects on the body:

Mechanism of Action:
Phosphodiesterase Type 5 (PDE5) Inhibition:
Sildenafil citrate, the active ingredient in Fildena 25 mg, is a PDE5 inhibitor. PDE5 is an enzyme found primarily in the smooth muscle cells of blood vessels in the penis and lungs.
By inhibiting PDE5, Sildenafil allows for increased levels of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells. This results in relaxation of the smooth muscle and dilation of blood vessels, particularly in the penis.
Increased blood flow to the penis during sexual stimulation helps in achieving and maintaining an erection.
Effects on Hormonal Regulation:
No Direct Effect on Hormones:
Sildenafil citrate does not directly alter hormone levels in the body. It does not affect the production or release of hormones such as testosterone, estrogen, or others involved in the body's endocrine system.
The mechanism of action of Sildenafil is localized to the vascular system and does not interfere with hormonal pathways.
Indirect Effects:
Enhancement of Nitric Oxide (NO) Pathway:
Sildenafil enhances the effects of nitric oxide (NO), a chemical messenger that plays a key role in dilating blood vessels and improving blood flow.
Nitric oxide is involved in various physiological processes, including the regulation of blood pressure and cardiovascular function, but it is not a hormone.
 

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