What is the mechanism of action of Sildigra XL Plus 150 Mg in the treatment of erectile dysfunction?
Sildigra XL Plus 150 Mg is a medication primarily used to treat erectile dysfunction (ED). Its active ingredient is sildenafil citrate, which works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). During sexual arousal, the release of nitric oxide (NO) in the corpus cavernosum of the penis leads to the activation of an enzyme called guanylate cyclase. This enzyme increases levels of cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscles in the blood vessels of the penis, allowing them to dilate and increase blood flow. This increased blood flow into the penis leads to an erection. However, PDE5 breaks down cGMP, leading to a decrease in its levels and consequently, the relaxation of smooth muscles is reduced, impairing the ability to achieve and maintain an erection. Sildenafil citrate in Sildigra XL Plus 150 Mg inhibits PDE5, which results in increased levels of cGMP, prolonged relaxation of the smooth muscles, and improved blood flow to the penis, facilitating the achievement and maintenance of an erection. It's worth noting that Sildigra XL Plus 150 Mg should be taken as directed by a healthcare professional, and it's essential to consider potential side effects and contraindications before use.  |
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